Effects of RvD1 on the concentrations of (a) TNF-α and (b) IL-6 in BALF of mice subjected to LPS-induced ALI. BALF samples were collected at 6 h, 12 h, and 24 h after LPS administration. RvD1 reduced the concentrations of TNF-α and IL-6 in BALF, and these effects were partially reversed by GW9662. Values are expressed as mean ± SD (n = 3). * p < 0.05 in comparison with the LPS group at each time point. # p < 0.05 in comparison with the LPS + RvD1 (600 ng) group at each time point.
Liao et al. Respiratory Research 2012 13:110 doi:10.1186/1465-9921-13-110